T.R.8.C.E.Open the app ›

Semaglutide Reconstitution & Dosage Calculator

Once-weekly GLP-1 receptor agonist for glucose control and weight loss, marketed as Ozempic and Wegovy.

Category
Metabolic
Half-life
~7 days
Best taken
In the morning
Common dose
0.25 mg
Open Semaglutide in the calculator ›

How to reconstitute Semaglutide

TR8CE uses one simple standard: 0.1 mL of bacteriostatic water per mg. A 5 mg vial takes 0.5 mL of water for a clean 10 mg/mL solution. Larger vials scale the water up to fit the glass.

Vial sizeBAC waterConcentration0.25 mg draws to
5 mg0.5 mL10 mg/mL2.5 units
10 mg1 mL10 mg/mL2.5 units
15 mg1.5 mL10 mg/mL2.5 units
20 mg2 mL10 mg/mL2.5 units
30 mg3 mL10 mg/mL2.5 units

Units are shown for a U-100 insulin syringe. A common starting dose is 0.25 mg. At 10 mg/mL, that draws to 2.5 units on a U-100 insulin syringe.

How Semaglutide works

Single-pathway GLP-1 receptor agonism enhances glucose-dependent insulin secretion, suppresses appetite, and delays gastric emptying.

Reported side effects

When is Semaglutide taken?

Semaglutide is commonly taken in the morning.

Frequently asked

How much bacteriostatic water do I add to Semaglutide?

Add 0.5 mL of bacteriostatic water to a 5 mg Semaglutide vial for a 10 mg/mL solution.

What is a common Semaglutide dose?

A common Semaglutide starting dose is 0.25 mg, which at 10 mg/mL draws to 2.5 units on a U-100 insulin syringe.

How do you reconstitute Semaglutide?

Draw bacteriostatic water into a syringe, inject it slowly down the inside glass of the Semaglutide vial (not onto the powder), and swirl gently until clear. Store refrigerated and use within the common window.

Related peptides

RetatrutideTirzepatideMOTS-cAOD-9604CagrilintideLipo-C
Research use only. The information on this page is for laboratory and educational reference. Research compounds are not for human consumption. TR8CE is a calculation and organization utility and does not provide medical advice. Reconstitution figures are common conventions, not prescriptions. Consult a qualified professional before making any health decision.